Vitamin D (25(OH)D) supplementation for physically active community-dwelling older women
DOI:
https://doi.org/10.5965/19847246242023e0122Keywords:
vitamin D supplementation, old women, physical and functional independenceAbstract
Knowing the serum levels of 25(OH)D and the bone profile of old women is relevant for the maintenance of physical and functional independence. Objective: To evaluate 25(OH)D supplementation in physically active old women. Methods: Intervention trial in groups. A total of 348 elderly women aged ≥ 60 years (67±5 years), practicing physical exercise for at least one year, at the Sesc Santana - Social Service of Commerce of São Paulo (SP) were evaluated. We compared 146 practitioners of Aquatic training (AT); 99 old women who practiced Multifunctional Gymnastics (GMF); and 103 old women who did not practice supervised physical exercise, who were classified as sedentary (SED). The old women with 25(OH)D levels below the median of the respective group were supplemented with cholecalciferol, 21,000 IU/week, for 12 months. Serum dosage of 25(OH)D, calculation of Body Mass Index (BMI) and Bone Densitometry (Dexa) were performed. The comparison of baseline data was performed using the univariate General Linear Model (GLM) and for the time of supplementation, the GLM for repeated measures, considering the significance level α<0.005. Results: Supplementation significantly increased 25(OH)D levels in AT (12.06±2.64 - 39.42±13.82 ng/mL - p<0.001), GMF (13.01±3.43 - 37.36±10.46 ng/mL - p<0.001) and SED (10.86±2.26 ng/mL - 38.30±13.77 ng/mL - p<0.001). There were no significant differences on the bone profile. Conclusion: The old women in the groups, even physically independent, presented osteopenia, osteoporosis and 25(OH)D deficiency, which was corrected after the supplementation protocol, showing its effectiveness.
Downloads
References
ADAMS, M. A. et al. Patterns of neighborhood environment attributes related to physical activity across 11 countries: A latent class analysis. Int J Behav Nutr Phys Act, [s. l.], v. 10, n. 34, p. 11-33. 2013.
AGOSTINI, D.; ZEPPA S. D.; LUCERTINI, F. et al. Muscle and bone health in postmenopausal women: role of protein and vitamin D supplementation combined with exercise training. Nutrients, [s. l.], v. 10, n. 8, e1103, 2018. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116194/. Acesso em: 23 abr. 2022.
BANCO INTERNACIONAL PARA A RECONSTRUÇÃO E O DESENVOLVIMENTO; BANCO MUNDIAL. Envelhecendo em um país mais velho. Washington: BIRD - Banco Mundial, 2011.
BILEZIKIAN, JP et al. Vitamin D: dosing, levels, form, and route of administration: does one approach fit all? Reviews in Endocrine and Metabolic Disorders, São Paulo, v. 22, p. 1201–1218, 2021.
BOUCHER, B. J. Vitamin D status and its management for achieving optimal health benefits in the elderly. Expert Review of Endocrinology & Metabolism, [s. l.], v. 13, n.6, p. 279-293, 2018. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/30317909. Acesso em: 23 abr. 2022.
BROE; K. E.; CHEN, T. C.; WEINBERG, J. et al. A higher dose of vitamin d reduces the risk of falls in nursing home residents: a randomized, multiple-dose study. J. Am. Geriatr. Soc., [s. l.], Feb; v. 55, n.2: 234-9. 2007. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/17302660. Acesso em: 22 abr. 2022.
CEGLIA, L. et al. A randomized study on the effect of vitamin D (3) supplementation on skeletal muscle morphology and vitamin D receptor concentration in older women. The Journal of Clinical Endocrinology and Metabolismo, [s. l.], v. 98, n. 12, p. E1.927-35, Dec. 2013.
CENTRO INTERNACIONAL DE LONGEVIDADE BRASIL. Envelhecimento ativo: um marco político em resposta à revolução da longevidade. 1. ed. Rio de Janeiro: [s. n.], 2015.
CONFORTIN, S. C. et al. (2020). Osteopenia/Osteoporosis and Its association with Sarcopenia: EpiFloripa aging study 2013/2014. Port J Public Health, [s. l.], v. 38, p. 15-22, 2020.
COSTA, G. et al. Estudo comparativo das adaptações fisiológicas agudas durante a execução de três variantes de um exercício básico de hidroginástica. Rev. Bras. Cineantropom. Desempenho Hum., [s. l.], v. 10, n. 4, p. 323-329, 2008.
DORING, M.; MORETTO, C. F.; DIEHL, A. A. et al. Envelhecimento humano: aspectos populacionais e de saúde na contemporaneidade. Passo Fundo: Universidade de Passo Fundo, 2018. 314 p.
FREITAS, C. et al. Intervalos de referência da vitamina D – 25(OH)D: posicionamento oficial da Sociedade Brasileira de Patologia Clínica/Medicina Laboratorial (SBPC/ML) e da Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) – Intervalos de Referência da Vitamina D - 25(OH)D. [s. l.: s. n.], 2017.
FRIED, L. P. et al. Risk factors for 5-year mortality in older adults. The Journal of American Medical Association, [s. l.], v. 279, n. 8, p. 622-623, 1998.
HOLICK, M. F. The vitamin D deficiency pandemic: approaches for diagnosis, treatment, and prevention. Endocr Metab Disord, [s. l.], v. 18, p. 153-165, 2017.
KALISCH, T. et al. Questionnaire-based evaluation of everyday competence in older adults. Clinical Interventions in Aging., [s. l.], v. 6, p. 37-46, 2011. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066251/. Acesso em: 23 abr. 2019.
KUCZMARSKI, M. F.; KUCZMARSKI, R. J.; NAJJAR, M. Descriptive anthropometric reference data for older Americans. J. Am. Diet. Assoc., [s. l.], v. 100, p. 59-66, 2002.
LACHMAN M. E. et al. When adults don’t exercise behavioral strategies to increase physical activity in sedentary middle-aged and older adults. Innovation in Aging., [s. l.], v. 2, n. 1, p. 1-12, 2018.
LEBRÃO, M. L.; DUARTE, Y. A. O. Sabe: saúde, bem-estar e envelhecimento: o projeto Sabe no município de São Paulo: uma abordagem inicial. Brasília: Organização Pan-Americana da Saúde, 2003. 255 p.
LIM, K.; THADHANI, R. Toxicidade da vitamina D. Braz. J. Nephrol. (J. Bras. Nefrol.), [s. l.], v. 42, n. 2, p. 238-244, 2020.
MOREIRA, P. F. P. Efeito da suplementação com colecalciferol no tecido adiposo de idosas ativas. 2015. Tese (Doutorado em Ciências) – Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, 2015.
MOREIRA, L. D. et al. High-intensity aquatic exercises (HydrOS) improve physical function and reduce falls among postmenopausal women. Menopause, São Paulo, v. 20, n. 10, p. 1012-1019, Oct. 2013.
MOREIRA-PFRIMER, L. D.; PEDROSA, M. A.; TEIXEIRA, L. et al. Treatment of vitamin D deficiency increases lower limb muscle strength in institutionalized older people independently of regular physical activity: a randomized double-blind controlled trial. Ann Nutr. Metab, [s. l.],v. 54, p. 291-300, 2009.
NASCIMENTO, N. A. P. et al. Effect of vitamin D level and physical exercise on the physical performance and functional test results in elderly women. J Geriatr Med Gerontol., São Paulo, v. 5, n.61, 2019.
NASCIMENTO, N. A. P. Efeito dos níveis de vitamina D e exercício físico no desempenho físico e funcional de idosas ativas, após suplementação com Colecalciferol. 2019. Tese (Doutorado em Ciências) – Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, 2019.
NASCIMENTO, N. A. P. et al. Relation among 25(OH)D, aquatic exercises, and multifunctional fitness on functional performance of elderly women from the community. J Nutr Health Aging, São Paulo, v. 2, n. 4, p. 376-82, 2016. DOI: 10.1007/s12603-015-0569-x.
PEREIRA, S. R. M.; CARVALHO DE MENDONÇA, L. M. Tratado de geriatria e gerontologia: osteoporose e osteomalácia. 4. ed. Rio de Janeiro: Guanabara Koogan, 2016.
ROSS, A. C.; MANSON, J. E.; ABRAMS, S. A. et al. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J. Clin. Endocrinol Metab., [s. l.], v. 96, p. 53-58, 2011.
ROSSI, E.; SADER, C. S. Tratado de geriatria e gerontologia: envelhecimento do sistema osteoarticular. 4. ed. Rio de Janeiro: Guanabara Koogan, 2016.
SESC. Serviço Social do Comércio. Realizações. São Paulo: [s. n.], 2011. 161 p.
WILLET, W. C. Nutritional epidemiology. 2. ed. New York: Oxford University Press, 1998.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 PerCursos
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
